Mookie Betts hit two home runs, including a game-ending, three-run blast in the 10th inning as the Los Angeles Dodgers rallied for an 8-5 victory over the visiting Detroit Tigers on Friday.

Freddie Freeman also homered for Los Angeles, while Michael Conforto and Will Smith had run-scoring hits in a five-run 10th to win it for the Dodgers. Los Angeles right-hander Yoshinobu Yamamoto had a career-best 10 strikeouts over five innings while allowing two runs.

Dodgers right-hander Luis Garcia (1-0) gave up two runs (one earned) in the top of the 10th but still earned the win.

Dillon Dingler had a homer and a two-run triple for the Tigers, and Gleyber Torres also homered as the Tigers dropped their second straight despite holding leads in each game. Detroit starter Jack Flaherty gave up two runs on three hits over 5 2/3 innings against his former team.

Detroit right-hander Beau Brieske (0-1) gave up five runs (four earned) while recording just one out in the 10th.

Trailing 5-3 in the 10th, the Dodgers pulled within a run on an RBI ground-rule double from Conforto followed by Smith’s game-tying single. Shohei Ohtani singled before Betts went deep for the second time. Betts had been doubtful for the series after losing nearly 20 pounds while dealing with a stomach virus for two weeks.

Los Angeles left-hander Tanner Scott gave up a game-tying single to Manuel Margot in the ninth.

In the 10th inning, Tigers automatic runner Riley Greene moved to third base on a ground out before Zach McKinstry was intentionally walked. Dingler tripled past a diving Conforto in left field for a 5-3 lead.

Freeman’s first home run of the season was a two-run shot in the sixth inning and came after the Dodgers entered the fifth without a hit against Flaherty.

The Dodgers opened the season 4-0 for the first time since 1981 — a year that ended with a World Series title.